The new drug acts as a clot-'buster'. [=it causes blood clots to break apart]
crime'-busters' [=people who stop crimes, who catch criminals, etc.]
Wait a minute, 'buster'. You're trying to trick me, aren't you?
(..) VINCENT: "Please" would be nice. WOLF: Come again? I said a "please" would be nice. Get it straight, buster. I'm not here to say "please." I'm here to tell you what to do. And if self-preservation is an instinct you possess... you better fucking do it (..)1994 Pulp Fiction