This latest setback has brought/carried/driven her 'to the depths of despair'.
We had begun to 'despair of' ever finding a house we could afford.
The people were 'driven to despair' by the horrors of war.
(..) Anna's... a goddess. You know what happens to mortals who get involved with the gods. - Buggered, is it ? - Every time. But don't despair. l think l have the solution to your problems. - Really ? - Mm-hmm. Her name is Tessa. She works in the Contracts Department. The hair, l admit, (..)1999 Notting Hill
(..) First there's this one. Cool, huh ? Yeah, it might make it hard to strike a really romantic note. Point taken. Don't despair. lf it's romance we're looking for, l believe l have just the thing. Yeah, well, there again, she might not think you had true love on your mind. Right. (..)1999 Notting Hill