We just bought a house here last month, and we're still 'getting to know' our neighbors. [=we're still meeting our neighbors; we're still becoming acquainted with our neighbors]
It's impossible to 'know' what will happen next. = There's 'no way of knowing' what will happen next. = There's 'no knowing' what will happen next.
This is the end of the organization 'as we know it'. [=the organization has changed and will never again be the same as it was]
(..) Oh, you act on me just like a tonic, Miss Scarlett. And will you tell me all the news... ...all the news of Miss Suellen? What's the matter, Miss Scarlett? Miss Suellen's not ill, is she? Oh, no, no. I thought surely she had written you. I guess she was ashamed to write you. She should be ashamed. (..)1939 Gone with the Wind
(..) It simply isn't done! Good heavens, woman, this is war, not a garden party! You've got to stay. Melanie needs you. Oh, bother Melanie. She's ill already. She shouldn't even be having a baby. She may have a difficult time. Well, can't we take her along? Do you want her to take that chance? (..)1939 Gone with the Wind