It's 'lonely at the top'. [=powerful and successful people often have few friends]
He was/felt 'lonely' without his wife and children.
the 'lonely hearts' section of the newspaper
(..) and he asked me if I'd take care of her while he's gone. - Take care of her? - No, man. Just take her out. You know, show her a good time. Make sure she don't get lonely. You're gonna be taking Mia Wallace out on a date? It is not a date. It's just like if you were going (..)1994 Pulp Fiction