They made it 'painfully' obvious/clear that we were not welcome. [=they made it very clear in a way that was rude or upsetting that we were not welcome]
His ankle is swollen and 'painful to the touch'. [=his ankle hurts if he touches it]
After the injury she was 'painfully' aware that her career in tennis would be over.
(..) Go ahead. We are family. We can drink together. Theres something the matter? The part of the only family left, I left Karen. Did you? I hope it wasn't too painful? How are things going, with you and Vonnie? It's okay. Although, she's got a little nervous, lately. Did she say anything? (..)2016 Café Society