With today's announcement, she has 'set the wheels in motion' for a run for the presidency. [=she has begun to run for president]
You could almost see the 'wheels' turning in his head. [=you could almost see him thinking about how to do something]
They hoped that the tax cuts would 'grease the wheels' of the economy. [=would help the economy work better]
(..) Come back here! Look at him go! Get him! BIFF: To the car! Go! GIRL: What's that thing he's on? BOY: A board with wheels. He's an absolute dream. THUG : Come on, come on! THUG : Look out for the car! BIFF: I'm going to ram him. ALL: Shit! (..)1985 Back to the Future