He 'abandoned' the principles that he once fought hard to defend.
He 'abandoned himself to' despair. [=he was overcome by despair]
The child had been 'abandoned' (by his parents) as an infant.
(..) - I was just dropping these off. Now, if you'll excuse me, they're putting me in something called Hero Squad. You have no idea what it's like to be abandoned by your son. Do you see my son? He chose his girlfriend over me. How the worm has turned. Look who feels the sting of an ungrateful child. (..)2004 TvShow: Arrested Development Title: Afternoon Delight Season: 2 Episode 6