His heart 'ached' [=he felt sad and sorry] for the children begging on the streets.
Symptoms of the flu include fever, general 'aches and pains', and sore throat.
She looked through the old pictures with a dull 'ache' in her heart.
(..) What? Can you steer the ship? No. I just finished driver's ed. Yes, of course, I can steer a ship. Well... why don't we give her a stomach ache? We'll escape through the gut. It just might work if it doesn't kill us first. You steer, I'll shoot. All hands below deck! (..)2013 Percy Jackson: Sea of Monsters