His heart 'ached' [=he felt sad and sorry] for the children begging on the streets.
Symptoms of the flu include fever, general 'aches and pains', and sore throat.
She looked through the old pictures with a dull 'ache' in her heart.
(..) Want to go for a walk? (SIGHS) What is it? Just before you went into the hospital, there was this... I felt an ache in my hip. So, I had a PET scan... and it lit up like a Christmas tree. The lining of my chest and my liver... (..)2014 The Fault in Our Stars