She lost her sight and is now learning to live with her/the 'affliction'.
He died from a mysterious 'affliction'.
her 'affliction' with polio
(..) He couldn't make sense of the letters. He reversed them in his head. The Maester said he'd heard tell of this affliction and that we simply must accept it. Ha! After that, I sat Jaime down (..)2012 TvShow: Game of Thrones Title: The Old Gods and the New Season: 2 Episode 6