She finally achieved/realized/fulfilled her 'life's ambition' [=the thing she most wanted to do in her life] when she started her own business.
He has 'ambitions' for an acting career. = He has 'ambitions' to become an actor. = His 'ambition' is to be/become an actor.
With her talent and fierce 'ambition' [=her very strong desire to succeed], she became a very successful actress.
(..) And yes, "Tesla" is merely the key to my dairy, not to my trick. You really think I'd part May you find solace for your forward ambition Tesla! Tesla! Alley! Alley! Tesla never made a machine like the one I asked for. (..)2006 The Prestige