She struggled with depression for years, but she's more 'centered' now and able to live a full life.
The investigation has 'centered' [='focused'] mainly 'on/upon' the alleged misuse of public funds.
She 'centers' her life 'on/around' her children. = Her life is 'centered on/around' her children.
(..) But I think it's really good that she's here. Cause we'll appreciate it more when she's gone? No, it's just...Look, you know, when I first moved to the city, I was a lot like her. I was spoiled, self- centered and you guys really took care of me. Yeah, Monica made us. Well, whatever. (..)2003 TvShow: Friends Title: The One Where Rachel's Sister Babysits Season: 10 Episode 5