She made some risky investments and 'in consequence' [='consequently'] lost a lot of money. = She lost a lot of money 'in consequence' of some risky investments.
Hundreds of people became sick 'as a consequence' [='as a result'] of the poor sanitary conditions.
The outcome of the election will be of little 'consequence' (to me). [=will not matter much to me]
(..) Brother. Thank you for coming. (fanfare) You are warned to stand by for an important announcement at .. This is news of the gravest consequence concerning the war with Eurasia. .. I'm very worried about the African front. The news is disquieting in the extreme. I've been worrying about it all day. (..)1984 1984