The team is looking to 'defend' its national title. [=to win the national title again]
As a U.S. senator, it is my responsibility to 'defend' [='uphold'] the Constitution.
She successfully 'defended' her championship. [=she won the championship again]
(..) I'm breaking the laws of nature, I know. Well, don't stop now. When the Sanctum's restored, they'll attack it again. - We gotta defend it. - Come on! Get up, Strange. Get up and fight! We can finish this. You can't fight the inevitable. Isn't it beautiful? (..)2016 Doctor Strange
(..) Your curiosity could have gotten you killed. You weren't manipulating the space-time continuum, you were breaking it. We do not tamper with natural law! We defend it. How did you know to do that? - Hm? Where did you learn the litany of spells required to even understand it? (..)2016 Doctor Strange