Examples

• The company's managers don't want to 'depart from' an approach that has worked well in the past. [=they do not want to change their approach]

• The actors were not allowed to 'depart from' the script. [=they were not allowed to say anything that was not in the script]

• The river 'departs' [='turns', 'deviates'] 'from' its original course a few miles downstream.