This latest setback has brought/carried/driven her 'to the depths of despair'.
We had begun to 'despair of' ever finding a house we could afford.
The people were 'driven to despair' by the horrors of war.
(..) by the time the last petal fell... the spell would be broken. If not, he would be doomed to remain a beast for all time. As the years passed... he fell into despair and lost all hope. For who could ever learn to love a beast? (ROOSTER CALLING) (SINGING) Little town (..)2017 Beauty and the Beast