This latest setback has brought/carried/driven her 'to the depths of despair'.
We had begun to 'despair of' ever finding a house we could afford.
The people were 'driven to despair' by the horrors of war.
(..) your enemy's squire. - Careful, Imp. - I've offended you. Forgive me, it's been a rough morning. Anyway, don't despair. I'm a constant disappointment to my own father and I've learned to live with it. - Your next tumble with Ros is on me. I'll try not to wear her out. (..)2011 TvShow: Game of Thrones Title: Cripples, Bastards, and Broken Things Season: 1 Episode 4