They are not getting married, 'despite' rumors to the contrary. [=even though there have been rumors saying they are getting married]
The law has yet to be passed, 'despite the fact that' most people are in favor of it.
They grew to love each other, almost 'despite themselves'.
(..) Then I realized we had done this same silly charade our entire lives. I tried to get my mind off how I was feeling. But I just felt stuck. I began to realize, despite all my powers, each and every citizen of Metro had something I didn't. A choice. Ever since I can remember I've always (..)2010 Megamind