His parents believed that the priesthood was his 'destiny'. [=that he would or should become a priest because fate or God intended it]
They were living in a time when expansion to the Pacific was regarded by many people as the 'Manifest Destiny' of the United States.
She felt that 'destiny' [='fate'] had decided that she would one day be President.
(..) Po? How many times do I have to kill the same stinking panda? Shen! A panda stands between you and your destiny. What? Prepare yourself for a hot serving of justice. Your reign of terror comes to an end. - What? (..)2011 Kung Fu Panda 2
(..) No! Yeah, like you could make me drink that. If I wanted you dead, I would have left you in that river. - Well, why save me? - So you can fulfil your destiny. What are you talking about? Where am I? What is this place? I'm surprised you remember so little. But you were so little when it happened. (..)2011 Kung Fu Panda 2