He looked 'familiar' [=he looked like someone I had seen before] but I couldn't remember his name.
Locals refer to the Maple Leaf restaurant 'familiarly' [='informally'] as ‘The Leaf.’
We are 'familiar with' the situation. [=we know about the situation]
(..) KATE: We have to be careful. -I agree. -But we have to try. KATE: Okay. All right, start with something small that we're familiar with. We should capture a Hydrobot, bring it in for testing. JOHN: Yeah. What is it, John? (..)2009 Terminator Salvation