Their plans for opening a restaurant 'came to grief' when they failed to get a loan.
He has been unable to recover from his 'grief' at/over his son's death.
“He's burned the toast.” “'Good grief'! Can't he do anything right?”
(..) Oh, I will do so. But I will also feel it as a man. Sinful Macduff! They were all struck for thee. Be this the whetstone of your sword. Let grief convert to anger. Blunt not the heart, enrage it. Gracious England hath lent us ten thousand men. Our power is ready. Our lack is nothing but our leave. (..)2015 Macbeth
(..) Stands Scotland where it did? Alas, poor country, it's almost afraid to know itself. It cannot be called our mother but our graves. What's our newest grief? Let not your ears despise my tongue which shall possess them with the heaviest sound that ever yet they heard. How does my wife? (..)2015 Macbeth