A powerful tornado 'wreaked havoc' on [=caused great destruction to] the small village.
Several small children can 'create/cause havoc' in a house.
The disease can 'play havoc' with the body's immune system.
(..) I bought myself a hospital full of doctors. You ought to be able to find one who can treat him. Here's something that'll interest you. "Narcotic shortages caused by the war wreak havoc here. A case in point... last night a man identified as a prominent New York doctor was arrested after breaking (..)2014 TvShow: The Knick Title: The Golden Lotus Season: 1 Episode 9