He is an 'institution' in local politics. [=he has participated in local politics for such a long time that people consider him to be a regular part of local politics]
She committed herself to a 'mental institution'. [=a hospital for people with mental or emotional problems]
The play has become something of an 'institution' on Broadway.
(..) And there's no family in the picture, is there? Not a wife Or children? So you've devoted your entire life To an institution that's now turning its back on you. The last illusion Of the illusionless man. (soft chuckle) (mutters) (..)2015 TvShow: Homeland Title: A False Glimmer Season: 5 Episode 12