The project has been tied up in political and legal 'knots' for years. [=nothing has happened with the project for years because of political and legal problems]
The mayor 'tied himself in knots' answering a touchy political question. [=he answered it in a confused or unclear way]
She 'knotted' a sweater around her shoulders. [=tied the sleeves of the sweater together around her shoulders]
(..) All right. Okay. Hey, Matt? Since I had to listen to endless hours of your storytelling this week, I need for you to do me a favor. You are gonna see a little girl with brown hair, very messy, lots of knots. She doesn't like to brush it. That's okay. Her name is Sarah. Can you please tell her (..)2013 Gravity