The project has been tied up in political and legal 'knots' for years. [=nothing has happened with the project for years because of political and legal problems]
The mayor 'tied himself in knots' answering a touchy political question. [=he answered it in a confused or unclear way]
She 'knotted' a sweater around her shoulders. [=tied the sleeves of the sweater together around her shoulders]
(..) Arm. Leg. I'm yours. Hot, isn't it? Viktor's gone to go and get drinks. Would you care to join us? No, we'd not care to join you and Viktor. What's got your wand in a knot? He's a Durmstrang. You're fraternizing with the enemy. The enemy? Who was it wanting his autograph? Besides, the whole point (..)2005 Harry Potter and the Goblet of Fire