It's 'lonely at the top'. [=powerful and successful people often have few friends]
He was/felt 'lonely' without his wife and children.
the 'lonely hearts' section of the newspaper
(..) He's just Dr Cox. He's always like that. Who really knows him? Who does he hang out with? - No one. - That must be lonely. ''Take two Turks as needed, apply to sensitive areas...'' Who wrote this? Whassup? Come on, Carla. Give me one good reason (..)2001 TvShow: Scrubs Title: My Mentor Season: 1 Episode 2