It's 'lonely at the top'. [=powerful and successful people often have few friends]
He was/felt 'lonely' without his wife and children.
the 'lonely hearts' section of the newspaper
(..) to score his pot and wag his pickle at coeds. You sound mad, Mom, mad enough to throw one of these little lady heads at him. - What's that supposed to mean? - Well, maybe you're a little bit lonely... and you're acting out for attention. That's ridiculous. I want you to move in with me. (..)2004 TvShow: Arrested Development Title: Afternoon Delight Season: 2 Episode 6