It's 'lonely at the top'. [=powerful and successful people often have few friends]
He was/felt 'lonely' without his wife and children.
the 'lonely hearts' section of the newspaper
(..) Yubaba doesn't want you in the bathhouse any longer. Where is your home? Don't you have any friends or family? No. No! I'm lonely. I'm lonely. What is it that you want? I want Sen. I want Sen! Take the gold. (..)2001 Spirited Away