Her family is 'lousy with' money. [=her family is very rich]
We could see that she was 'feeling lousy'. [='feeling ill']
He is 'lousy' [='terrible'] 'at' sports/math/cooking.
(..) - Where is she? - No. - Maybe you'd like to tell the police. - Why don't we call the police? Why don't we call them and tell them what a lousy father you are... and that they should lock you up for beating your daughter? What? I never beat her. Is that what she told you? (..)1996 Foxfire