I'm sorry to be such a 'nuisance' [=I'm sorry to bother you], but I need your help again.
The sticky clay was a 'nuisance' to work with. [=was difficult to work with]
He 'made a nuisance of himself'. [=he behaved in an annoying way]
(..) your parenting troubles are over, yes. Congratulations, Stoick! Everyone is so relieved! Out with the old and in with the new, right? - No one will miss that nuisance! - We're throwing a party to celebrate! - Come over here. - Hurry! He's gone? Most afternoons, but who can blame (..)2010 How to Train Your Dragon