I'm sorry to be such a 'nuisance' [=I'm sorry to bother you], but I need your help again.
The sticky clay was a 'nuisance' to work with. [=was difficult to work with]
He 'made a nuisance of himself'. [=he behaved in an annoying way]
(..) Are you all right? You're not all right, are you? Is it this contest thing that you're in still or... I'm sorry, I am being a nuisance. I should go. No, it's okay. We can talk. I'll put some clothes on. I'll be right back. Do you have an aspirin? Can I get you something to drink with this? (..)1997 The Game