They made it 'painfully' obvious/clear that we were not welcome. [=they made it very clear in a way that was rude or upsetting that we were not welcome]
His ankle is swollen and 'painful to the touch'. [=his ankle hurts if he touches it]
After the injury she was 'painfully' aware that her career in tennis would be over.
(..) didn't realize that they succeeded. If it really is CPH, in this quantity, I'm amaze you're still alive. Not for long. Learning is always a painful process. Like when you're little, your bones are growing and you ached all over. Can you believe I can remember the sound of my own bones growing? (..)2014 Lucy