They made it 'painfully' obvious/clear that we were not welcome. [=they made it very clear in a way that was rude or upsetting that we were not welcome]
His ankle is swollen and 'painful to the touch'. [=his ankle hurts if he touches it]
After the injury she was 'painfully' aware that her career in tennis would be over.
(..) of us are the same as we were a moment ago and... we should not try to be, because it is just... - Painful. - Yeah. Yeah, that sounds painful. So what you feel like,Samantha? It's just... (..)2013 Her