They made it 'painfully' obvious/clear that we were not welcome. [=they made it very clear in a way that was rude or upsetting that we were not welcome]
His ankle is swollen and 'painful to the touch'. [=his ankle hurts if he touches it]
After the injury she was 'painfully' aware that her career in tennis would be over.
(..) Shit. No one wants to read about kids getting raped by Priests, especially now. But you asked a lot of people to relive some very painful experiences, and you just disappear. Phil, you know why we were taken off of this story. It's been six weeks since /. (..)2015 Spotlight
(..) Oh, well, thanks, Ben. I think. Although I take issue with your reference to my seniority, I will say that Stewart's departure is especially painful for me. Because for... what, Stewart? Twenty years now? Stewart's been more than willing to part with his money at the poker table. (..)2015 Spotlight