You don't know anything about my situation, and yet you have the 'presumption' [=(more commonly) 'gall, nerve'] to tell me what to do!
Thousands of people used this drug 'on the presumption that' it was safe. [=they used it because they believed that it was safe]
The trial was unfair from the beginning because there was no 'presumption of' innocence.
(..) Really, Walt. What happened? Because this isn't you. What would you know about me, Gretchen? What would your presumption about me be, exactly? That I should go begging for your charity? And you waving your chequebook around... (..)2009 TvShow: Breaking Bad Title: Peekaboo Season: 2 Episode 6