Computer technology has made 'profound' [='major, significant'] changes in our lives.
His paintings have had a 'profound' effect/impact/influence on her own work.
Her books offer 'profound' insights into the true nature of courage.
(..) if I'm barking up the right tree. You care about me, Stan. You would go to great trouble for me. OK, we're getting somewhere. Our friendship is so profound, it's like a love. Aw. Our love is developing a sexual component? GLASS SMASHES (..)2019 TvShow: American Dad! Title: One-Woman Swole Season: 13 Episode 14