He's 'having a rough time (of it)'. = He's 'going through a rough time'. [=he is having a difficult time; his life has been difficult recently]
The project still has a few 'rough edges'. [=the project still has a few things that need to be changed or finished]
Don't 'be so rough on them' [=don't punish or criticize them so harshly] for making a mistake.
(..) You can do anything with her... come on her, f$ck her in the mouth, f$ck her in the ass, come on her face. She'll get your cock so hard, she'll make it explode. But no rough stuff. All right? All right, I'll take it. Hey, man! Take out no money over here. You gonna f$ck me? You're gonna f$ck her. (..)1976 Taxi Driver
(..) You run all over town, don't you? Travis? - You run all over town, don't you? - Yeah. I mean, you handled some pretty rough customers. Yeah, I have. - You carry a piece? - No. - You need one? - No. (..)1976 Taxi Driver