She has a reputation for being 'good/great in the sack'. [=for being a good sexual partner]
He's ready to 'jump/climb in the sack' [=have sex] with any woman who'll have him.
The company 'gave him the sack' [=fired him] for improper conduct.
(..) Sorry, Sheldon, it's just not a good time for playing games. This is a game to you? Uh, was the Battle of Antietam a game? Huh? Was the sack of Rome a game? Yes, no and no. Wait. I just want you all to know that I forgive you. (..)2011 TvShow: The Big Bang Theory Title: The Skank Reflex Analysis Season: 5 Episode 1