In the most 'severe' cases, the disease can lead to blindness.
He's very generous despite his somewhat 'severe' manner.
The accident has 'severely' limited her mobility.
(..) get back to your work! I thought I saw you. Oh, God. You know? I did stop home on Friday, come to think of it. I had this severe headache and was in the neighborhood, so I... darted into the house to get some aspirin. Where were you, Laura? I didn't see you. (..)1992 Twin Peaks: Fire Walk with Me