She tried to 'put on a brave face' [=she tried to appear brave or calm] despite the pain of the injury.
You can refuse to talk to her if you like, but you're just 'cutting off your nose to spite your face'.
They made it on time 'in spite of the fact' that they got a flat tire.
(..) I leave you. Well, all that's no good. You see, 'cause... none of those options get me you. And in spite of everything, I love you. I love you too. I meant what I said when I gave you that ring. I did too. (..)2004 The Notebook