She tried to 'put on a brave face' [=she tried to appear brave or calm] despite the pain of the injury.
You can refuse to talk to her if you like, but you're just 'cutting off your nose to spite your face'.
They made it on time 'in spite of the fact' that they got a flat tire.
(..) room in his shop last night and discovered this. It's empty, but we found traces of the PX- serum in it. He's our man. So, somehow, in spite of your incompetence, we solved this one. I was framed! You won't get away with this! Get your mitts off of me! I am a legitimate businessman. (..)2013 Despicable Me 2