The 'odds are stacked against' you. [=the odds are against you; you do not have a good or fair chance of winning, succeeding, etc.]
There are things you can do to 'stack the odds' in your favor. [=to make it more likely for you to win, succeed, etc.]
In many ways, the 'cards are stacked against' immigrants. [=immigrants face unfair and difficult circumstances]
(..) Okay, finally, Kirk-- he can't take it anymore. He yorks. Now it's just down to Chekov and Spock. But Chekov, you see, he's got a whole fat stack of Quatloos riding on this, and he has figured out a way to win. He's got Scotty back in the transporter room, (..)2013 TvShow: Breaking Bad Title: Blood Money Season: 5 Episode 9