The language is 'unfamiliar to' him. [=he does not know the language at all]
His 'unfamiliarity' with the language made the trip very challenging.
He gets nervous when he is in 'unfamiliar' surroundings.
(..) use new eggs. hi. Hey,I'm running out to the market. Do you guys need anything? Oh,well,this would be one of those circumstances that people unfamiliar with the law of large numbers would call a coincidence. I'm sorry? I need eggs. Four dozen should suffice. Four dozen? (..)2007 TvShow: The Big Bang Theory Title: The Luminous Fish Effect Season: 1 Episode 4