He's been 'unlucky in love'. [=he has had a series of bad romantic relationships]
She was 'unlucky' enough to get a flat tire on the way to her job interview.
He thinks it's 'unlucky' to have a black cat cross your path.
(..) The Corleone family wants to buy me out? No, I buy you out. Your casino loses money. We can do better. - You think I'm skimming off the top? - You're unlucky. You Guineas make me laugh. I took Freddy in when you had a bad time, and now you try to push me out! You did that (..)1972 The Godfather
(..) because of this Sollozzo business. And I have to make arrangements to bring him back here safely. Cleared of all these false charges. But I'm a superstitious man. If an unlucky accident should befall him, if he should be shot by a police officer, or if he should hang himself in his jail cell, (..)1972 The Godfather