The painkillers 'wore off' [=stopped having an effect; stopped decreasing or removing pain] after a couple of hours.
As their visit 'wore on' [='dragged on'] she started hinting that it was time to leave.
All that work in the yard yesterday really 'wore' me 'out'.
(..) Only love can break it. Come, now. Can you please turn these two back into their normal forms? The spell on those two wore off long ago. Change back if you want. I don't get along with my sister. She's so obnoxious. You saw how tacky her home is. We're identical twins, (..)2001 Spirited Away