Even though the rumor was false, it 'wrecked' [='ruined'] her career.
Dad was a 'nervous wreck' on the day I had my surgery.
The stress of her final exams made her a 'wreck'.
(..) l don't wanna be an actor. Stromboli was terrible. - He was? - Yeah, he locked me in a bird cage-- - He did? - Uh-huh, but l learned my lesson. - l'm going-- - Oh, you poor, poor boy. You must be a nervous wreck. That's it, you are a nervous wreck! We must diagnose this case at once. Bless my soul. (..)1940 Pinocchio